The Gotthard Pass counts among the most important Alpine crossings in Europe. The story of its development from a small path across the high mountains to the longest railway tunnel on earth relates the struggle of mankind to create a faster and safer way to the south. It cost many lives, but it also provided many jobs and gave hope of a better future. Today, the consequences of the climate change affect the life on Mount Gotthard more than the dangers of high mountains. In fact, global warming makes the glaciers melt and threatens the stability of rock slopes in high mountain regions. The unfreezing of the permafrost can cause the dissemination of unknown and maybe even harmful micro-organisms all over Europe. The story of the pass is not over yet.